Pyruvate

Maryposa · 01-31-2009, 04:25 PM

I was thinking of taking a Pyruvate supplement.
Then I read it is a product of sugar metabolism. Um, that scared me. I am no ignorante but when I read the phrase "sugar metabolism" well... my reaction is

Anyone want to enlighten me as to why this is a good supplement to take???

Maryposa · 02-02-2009, 02:01 PM

No one??

kimlou · 02-02-2009, 04:16 PM

Quote:

Originally Posted by Maryposa

No one??

No help here, sorry.

Hopefully Fawn or someone will stop in .

Maryposa · 02-02-2009, 04:18 PM

Well, thanks for responding

keikei · 02-02-2009, 04:45 PM

Hi Maryposa! I'm no expert but I did get a 4.0 in my biochem course last quarter and it was aaaaaaaaaaalllllllll about sugar metabolism!

Pyruvate is the end product of glycolysis, or the breakdown of glucose. The body breaks it down into a compound called acetyl-coA, which is then run through a bunch of other cycles, turned into a whole lot of energy, and eventually broken down into CO2.

Incidentally your body degrades fat into acetyl-coA to run the same set of reactions, so I would think that feeding your body more pyruvate would provide an alternate source of acetyl-coA, thereby taking away that need to get acetyl-coA from fat. And we don't want that! The whole point of lowcarbing is to deprive your body of carbs so that it's forced to get energy from fat.

As i said before, I'm nooooo expert at all but that's just my take on it. I googled pyruvate supplementation and I didn't see anything about it being compatible with LC diets, just about energy boosts (for the reasons I mentioned above--pyruvate is just extra fuel for cells).

Any experts, feel free to weigh in! I hope that was helpful, though.

fawn · 02-02-2009, 06:15 PM

Pyruvate put simply transports glucose to muscles. It's a compound found in the apple. Just had one with 2 string cheeses for lunch today!

Quote:

Hi Maryposa! I'm no [COLOR="Red"]expert[/COLOR] but I did get a 4.0 in my biochem course last quarter

Oh yes you are!!! a 4.0 congratulations!!!!

Nursie_Stacie · 02-02-2009, 06:38 PM

I take 1000mg of Calcium Pyruvate daily. I have for about a year now and I think it has many health and weight loss benefits. I was actually seeing a nutritionist speciallising in low carb who recommended this.

I'm curious keikei what is the reasoning behind it possibly not supporting a low carb woe? It has not seemed to hinder me at all, I actually feel alot better when taking it.

Always something new to learn .

Maryposa · 02-03-2009, 09:17 AM

Thank you! Well, I think you are closer to expert than most!

Quote:

Originally Posted by keikei

Hi Maryposa! I'm no expert but I did get a 4.0 in my biochem course last quarter and it was aaaaaaaaaaalllllllll about sugar metabolism!

Pyruvate is the end product of glycolysis, or the breakdown of glucose. The body breaks it down into a compound called acetyl-coA, which is then run through a bunch of other cycles, turned into a whole lot of energy, and eventually broken down into CO2.

Incidentally your body degrades fat into acetyl-coA to run the same set of reactions, so I would think that feeding your body more pyruvate would provide an alternate source of acetyl-coA, thereby taking away that need to get acetyl-coA from fat. And we don't want that! The whole point of lowcarbing is to deprive your body of carbs so that it's forced to get energy from fat.

As i said before, I'm nooooo expert at all but that's just my take on it. I googled pyruvate supplementation and I didn't see anything about it being compatible with LC diets, just about energy boosts (for the reasons I mentioned above--pyruvate is just extra fuel for cells).

Any experts, feel free to weigh in! I hope that was helpful, though.

Maryposa · 02-03-2009, 09:23 AM

Quote:

Originally Posted by fawn

Pyruvate put simply transports glucose to muscles. It's a compound found in the apple. Just had one with 2 string cheeses for lunch today!

Oh yes you are!!! a 4.0 congratulations!!!!

OK, so we want to transport glucose to muscles, right?

Maryposa · 02-03-2009, 09:24 AM

Quote:

Originally Posted by Nursie_Stacie

I take 1000mg of Calcium Pyruvate daily. I have for about a year now and I think it has many health and weight loss benefits. I was actually seeing a nutritionist speciallising in low carb who recommended this.

I'm curious keikei what is the reasoning behind it possibly not supporting a low carb woe? It has not seemed to hinder me at all, I actually feel alot better when taking it.

Always something new to learn .

Did he nutritionist explain WHY it was recommended?

SlapHappy · 02-03-2009, 09:36 AM

Pyruvate has been shown to be useful for weight loss if you take 30 to 60 GRAMS of it per day. At dosages lower than that no one can find any benefits.

Nursie_Stacie · 02-03-2009, 09:40 AM

I actually do not remember her full explanation. I was having so many problems at the time . When I made my first visit with her I was what I felt my last rope. I had become so carb sensitive/Intolerant from staying very low carb for so long I could not add any carbs back with out significant weight gain.

She basically reinducted me properly and aded some supplements. I had very low energy, had lost a lot of muscle, and she was worried about possible future osteoporosis issues. I was taking initially 2 tablets, 3 times a day and with in a week I started feeling a difference and I took that dose through out my first 30 lbs of weight loss then weaned down slowly to one a day. In weight loss mode I can feel a difference when I'm on it.

Before I posted this I went a goggled itto refresh my memory and it solidifies the reasoing why she put me on it. Seems to have many benefits.

Maryposa · 02-03-2009, 09:50 AM

Quote:

Originally Posted by Nursie_Stacie

I actually do not remember her full explanation. I was having so many problems at the time . When I made my first visit with her I was what I felt my last rope. I had become so carb sensitive/Intolerant from staying very low carb for so long I could not add any carbs back with out significant weight gain.

She basically reinducted me properly and aded some supplements. I had very low energy, had lost a lot of muscle, and she was worried about possible future osteoporosis issues. I was taking initially 2 tablets, 3 times a day and with in a week I started feeling a difference and I took that dose through out my first 30 lbs of weight loss then weaned down slowly to one a day. In weight loss mode I can feel a difference when I'm on it.

Before I posted this I went a goggled itto refresh my memory and it solidifies the reasoing why she put me on it. Seems to have many benefits.

Thanks... ya I googled it too but a lot of it talks about sugar metabolism and I am wondering if I want to help my sugar metabolism along. But if what it does is transport energy to muscles than ya, I can accept that

Thanks for your replies!

Maryposa · 02-03-2009, 09:51 AM

Quote:

Originally Posted by SlapHappy

Pyruvate has been shown to be useful for weight loss if you take 30 to 60 GRAMS of it per day. At dosages lower than that no one can find any benefits.

And how many apples would that be? lol

Thanks for the reply.

afuentes · 02-03-2009, 09:52 AM

I took calcium pyruvate a while ago. It was helpful but I took it in a very pure form and it was expensive!!!!!!

Maryposa · 02-03-2009, 09:52 AM

Quote:

Originally Posted by fawn

Pyruvate put simply transports glucose to muscles. It's a compound found in the apple. Just had one with 2 string cheeses for lunch today!

Oh yes you are!!! a 4.0 congratulations!!!!

PS Yes I knew it was from apples, I did find information on it, the thing that I was focusing on here is what it means by "sugar metabolism".... so thanks for your explaination about transporting glucose to muscles.

AnonomissX · 02-03-2009, 10:01 AM

Everyone correct me if I'm wrong...

If pyruvate is the part that helps transport the blood glucose into the muscle, then its not the SOURCE (ie carbohydrates vs fats) but the END RESULT (ie the broken down source into blood glucose) that the pyruvate helps.

So....if you are training your body through LC to burn the fat instead of the carbohydrate for fuel, and that fuel is the blood glucose that it is making from that fuel source...then pyruvate is just one of the end helpers?

Anyone remember Covert Bailey of "Fit or Fat"? I remember him speaking of ATP and pyruvate....but my head hurts from a fresh read of Dr Barry Sears "Toxic Fat" and he touches a LOT on the ATP cycle

Maryposa · 02-03-2009, 10:03 AM

That is what I am peicing together as I read more. Thanks.

Quote:

Originally Posted by AnonomissX

Everyone correct me if I'm wrong...

If pyruvate is the part that helps transport the blood glucose into the muscle, then its not the SOURCE (ie carbohydrates vs fats) but the END RESULT (ie the broken down source into blood glucose) that the pyruvate helps.

So....if you are training your body through LC to burn the fat instead of the carbohydrate for fuel, and that fuel is the blood glucose that it is making from that fuel source...then pyruvate is just one of the end helpers?

Anyone remember Covert Bailey of "Fit or Fat"? I remember him speaking of ATP and pyruvate....but my head hurts from a fresh read of Dr Barry Sears "Toxic Fat" and he touches a LOT on the ATP cycle

01-31-2009, 04:25 PM	#1
Maryposa Moderator Join Date: Jul 2008 Location: Orange County, CA Posts: 6,774 Gallery: Maryposa Stats: 355/181.0/155 169.4 VFT! WOE: Weight loss surgery (VSG) + Low Carb + Exercise Start Date: 1998; Restart May 2007 @355; WLS March 2010	Pyruvate I was thinking of taking a Pyruvate supplement. Then I read it is a product of sugar metabolism. Um, that scared me. I am no ignorante but when I read the phrase "sugar metabolism" well... my reaction is Anyone want to enlighten me as to why this is a good supplement to take??? Last edited by Maryposa; 01-31-2009 at 04:26 PM..

02-03-2009, 09:40 AM	#12
Nursie_Stacie Major LCF Poster! Join Date: May 2006 Location: Arkansas But my heart will always be in Fl. Posts: 1,505 Gallery: Nursie_Stacie Stats: 224/170/155 39 years old WOE: Atkins Tweeked	I actually do not remember her full explanation. I was having so many problems at the time . When I made my first visit with her I was what I felt my last rope. I had become so carb sensitive/Intolerant from staying very low carb for so long I could not add any carbs back with out significant weight gain. She basically reinducted me properly and aded some supplements. I had very low energy, had lost a lot of muscle, and she was worried about possible future osteoporosis issues. I was taking initially 2 tablets, 3 times a day and with in a week I started feeling a difference and I took that dose through out my first 30 lbs of weight loss then weaned down slowly to one a day. In weight loss mode I can feel a difference when I'm on it. Before I posted this I went a goggled itto refresh my memory and it solidifies the reasoing why she put me on it. Seems to have many benefits. __________________ Life isnt like a box of chocolates..its more like a jar of jalapenos. What you do today, might burn your ass tomorrow ! Before/ After pics http://www.lowcarbfriends.com/photop...111418/cat/500

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02-02-2009, 02:01 PM	#2
Maryposa Moderator Join Date: Jul 2008 Location: Orange County, CA Posts: 6,774 Gallery: Maryposa Stats: 355/181.0/155 169.4 VFT! WOE: Weight loss surgery (VSG) + Low Carb + Exercise Start Date: 1998; Restart May 2007 @355; WLS March 2010	No one??

02-02-2009, 04:18 PM	#4
Maryposa Moderator Join Date: Jul 2008 Location: Orange County, CA Posts: 6,774 Gallery: Maryposa Stats: 355/181.0/155 169.4 VFT! WOE: Weight loss surgery (VSG) + Low Carb + Exercise Start Date: 1998; Restart May 2007 @355; WLS March 2010	Well, thanks for responding

02-02-2009, 04:45 PM	#5
keikei Junior LCF Member Join Date: Feb 2009 Location: Seattle, WA Posts: 11 Gallery: keikei Start Date: Jan 2009	Hi Maryposa! I'm no expert but I did get a 4.0 in my biochem course last quarter and it was aaaaaaaaaaalllllllll about sugar metabolism! Pyruvate is the end product of glycolysis, or the breakdown of glucose. The body breaks it down into a compound called acetyl-coA, which is then run through a bunch of other cycles, turned into a whole lot of energy, and eventually broken down into CO2. Incidentally your body degrades fat into acetyl-coA to run the same set of reactions, so I would think that feeding your body more pyruvate would provide an alternate source of acetyl-coA, thereby taking away that need to get acetyl-coA from fat. And we don't want that! The whole point of lowcarbing is to deprive your body of carbs so that it's forced to get energy from fat. As i said before, I'm nooooo expert at all but that's just my take on it. I googled pyruvate supplementation and I didn't see anything about it being compatible with LC diets, just about energy boosts (for the reasons I mentioned above--pyruvate is just extra fuel for cells). Any experts, feel free to weigh in! I hope that was helpful, though.

02-02-2009, 06:38 PM	#7
Nursie_Stacie Major LCF Poster! Join Date: May 2006 Location: Arkansas But my heart will always be in Fl. Posts: 1,505 Gallery: Nursie_Stacie Stats: 224/170/155 39 years old WOE: Atkins Tweeked	I take 1000mg of Calcium Pyruvate daily. I have for about a year now and I think it has many health and weight loss benefits. I was actually seeing a nutritionist speciallising in low carb who recommended this. I'm curious keikei what is the reasoning behind it possibly not supporting a low carb woe? It has not seemed to hinder me at all, I actually feel alot better when taking it. Always something new to learn .

02-03-2009, 09:36 AM	#11
SlapHappy Senior LCF Member Join Date: Jan 2009 Location: Eastern Washington Posts: 327 Gallery: SlapHappy Stats: 330/202/185 WOE: LC Start Date: 12/07/98	Pyruvate has been shown to be useful for weight loss if you take 30 to 60 GRAMS of it per day. At dosages lower than that no one can find any benefits.

02-03-2009, 09:52 AM	#15
afuentes Very Gabby LCF Member!!! Join Date: May 2007 Location: Las Vegas, Nevada Posts: 4,985 Gallery: afuentes Stats: 188/130/128 - I am 5'6" WOE: Primal/low carb with weight training Start Date: honest restart - 11/20/08	I took calcium pyruvate a while ago. It was helpful but I took it in a very pure form and it was expensive!!!!!!

02-03-2009, 10:01 AM	#17
AnonomissX Junior LCF Member Join Date: Jan 2009 Location: Las Vegas, NV Posts: 28 Gallery: AnonomissX	Everyone correct me if I'm wrong... If pyruvate is the part that helps transport the blood glucose into the muscle, then its not the SOURCE (ie carbohydrates vs fats) but the END RESULT (ie the broken down source into blood glucose) that the pyruvate helps. So....if you are training your body through LC to burn the fat instead of the carbohydrate for fuel, and that fuel is the blood glucose that it is making from that fuel source...then pyruvate is just one of the end helpers? Anyone remember Covert Bailey of "Fit or Fat"? I remember him speaking of ATP and pyruvate....but my head hurts from a fresh read of Dr Barry Sears "Toxic Fat" and he touches a LOT on the ATP cycle