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Old 03-08-2013, 12:41 AM   #1
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JUDDD was on the news today

Well not exactly, they did show someone cutting up an apple and saying that calorie restrictive diets bring about SIRT1..but still.. great to see this becoming more out in the mainstream, especially on our local news.

It was a story about Resveratrol and new research and how close they are getting to a similar artificial compound but more powerful. Resveratrol provokes similar reactions as calorie restrictive diets they say. (It's not going to happen soon though).

They say SIRT1 is like a Pac-Man that removes and breaks up certain proteins and tells other proteins to go out and repair the cells. When SIRT1 was active, miraculous things seemed to happen.

I'm thrilled about this because it will further strengthen the science behind JUDDD and hopefully we can learn more now, especially as Dr J has gone MIA, although some of the JB's here are trail blazing by their own experiences. Great news though!
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Old 03-08-2013, 04:32 AM   #2
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This was on your local news? That is great. If you find a clip I'd love to see it.
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Old 03-08-2013, 05:13 AM   #3
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Carly if you google "resveratrol news" you will see the latest media reports
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Old 03-08-2013, 09:55 AM   #4
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I hope they do some studies soon, to find out if IF is beneficial to ward off, or even cure disease.
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Old 03-08-2013, 10:14 AM   #5
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Cool! When I googled it I got this article written just 19 minutes ago for the LA Times.

It talks about sirtuins.

Scientists shed light on how resveratrol works - latimes.com
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Old 03-08-2013, 10:25 AM   #6
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There are many recent articiles about this, and a recent one in the LA Times science section. David Sinclair was involved in the initial studies years ago, however I found this info below but see where I have highlighted below. The drugs don't affect weight loss but this could be incorrect reporting as I'm sure there were some fat rodents that were involved.

IT sounds too good to be true, but a respected Australian scientist believes he has invented a new class of superdrug that could prevent cancer and Alzheimer's disease.
What's more, Professor David Sinclair says his drugs have the potential to help some people enjoy a healthy life until the age of 150. However, this needs further research.
A paper in the March 8 issue of the journal, Science, explains how the drugs have the ability to switch on the body's defences against ageing.
Three of the drugs are in human trials for the treatment of specific illnesses such as type 2 diabetes and inflammatory bowel disease, says the University of New South Wales geneticist.
Prof Sinclair is most excited about the potential to prevent illness and hopes to prove the drugs will have a dual purpose of treating and preventing disease at the same time.
"My research has been criticised because it sounds too good to be true. This paper shows it is true," he says in a telephone interview from Harvard Medical School, where he is based.
Prof Sinclair's drugs target the enzyme SIRT1, which is switched on naturally by calorie restriction and exercise, but it can also be enhanced through activators such as resveratrol in red wine.
He and his colleagues have developed 4000 synthetic activators. Each one is 100 times more potent than a glass of red wine and the best three are the ones in human trials.
"Our drugs can mimic the benefits of a healthy diet and exercise, but there is no impact on weight," says Prof Sinclair, who suggests the first medicine to be marketed could be for diabetes in about five years.
Once a significant number of people are using the drugs, it will be possible to assess other benefits.
"We can look at 10,000 people and see if they are healthier and living longer than the general population."
In animal tests, overweight mice given synthetic resveratrol were able to run twice as far as slim mice and they lived 15 per cent longer.
"My prediction is that we will delay the onset of diseases and will not have so many people becoming chronically sick in their 50s and 60s," says Prof Sinclair.
The hope is that people will live healthily into their hundreds.
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Old 03-08-2013, 10:26 AM   #7
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Ha Yam Yam..we posted at the same time
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Old 03-08-2013, 10:36 AM   #8
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Originally Posted by mojocat View Post
Ha Yam Yam..we posted at the same time
Great minds think alike...at the same time...
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Old 03-08-2013, 10:44 AM   #9
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David Sinclair, 40

Professor of pathology, Harvard Medical School

What he does: Has taken resveratrol, a compound found in the skin of red grapes, since 2003. He has even gotten his wife and parents to follow suit.

Why: Resveratrol may activate a family of longevity-related enzymes. Sinclair gave up a calorie-restricted diet, which may work similarly, after a week. "It just made life seem longer," he says.
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Old 03-08-2013, 11:23 AM   #10
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Quote:
Originally Posted by mojocat View Post
David Sinclair, 40


Why: Resveratrol may activate a family of longevity-related enzymes. Sinclair gave up a calorie-restricted diet, which may work similarly, after a week. "It just made life seem longer," he says.
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Old 03-08-2013, 01:30 PM   #11
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Old 03-08-2013, 06:19 PM   #12
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Old 03-08-2013, 08:53 PM   #13
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Quote:
Originally Posted by mojocat View Post
David Sinclair, 40

Professor of pathology, Harvard Medical School

What he does: Has taken resveratrol, a compound found in the skin of red grapes, since 2003. He has even gotten his wife and parents to follow suit.

Why: Resveratrol may activate a family of longevity-related enzymes. Sinclair gave up a calorie-restricted diet, which may work similarly, after a week. "It just made life seem longer," he says.
Not tough enough to be a JUDDD BUDD, eh, buddy?
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Old 03-08-2013, 09:19 PM   #14
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Hehehe and he's solved the longevity puzzle... JUDDD made life seem longer...the irony in that.
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Old 03-09-2013, 07:44 AM   #15
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He was interviewed on Science Friday on NPR yesterday and I'm sure you can find the interview on their website.

And Dr. Mosley was on ABC news interviewed by Juju Chang - twice. Once was (my memory) Feb 27 and the other was March 2 or 3. The segments are on the ABC news website.
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