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Old 07-10-2013, 06:27 PM   #1
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I can't take it anymore!! (TMI)

I was diagnosed t2 April 2010, taking Metformin ever since. The entire time I've had frequent bouts of raging diarrhea and cramping. I have had times where it didn't bother me much, but those days are very rare. At it's worst, I try not to go anywhere other than work for fear that I will not be able to make it to a restroom.

Just recently I tried the ER version to see if it would help ease those symptoms, and have found it does not. Today has been soooo bad. I have a cold, so I sneeze .. and squirt! I cough .. and squirt! Each time I run to the bathroom to make sure I haven't gone on myself. I cannot take this anymore!! At the last visit, my dr said she could prescribe januvia, but I haven't heard very good things about it.

I don't know what to do about this. I am not a point diet-wise where I can do without meds, but I can't keep living like this. What is a good medication I can take that doesn't cost a fortune plus potentially give me cancer or a heart attack?
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Old 07-10-2013, 07:19 PM   #2
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You are describing my life for the last 14 months. I couldn't go anywhere without knowing exactly where the bathroom was and taking extra clothes with me. Work was also a nightmare as the closest bathroom is on the other side of the building. I could be fine one minute and then all of a sudden, WHAM, it hit me and I had to be in the bathroom NOW. Absolutely no warning and totally uncontrollable.
I kept thinking it was something I was eating and kept experimenting with foods and what time I ate them. I was afraid to eat anything before going to work. But, I also had the issue even if I didn't eat anything.
I didn't want to give up the met because I didn't like any of the alternatives, but it got to the point I just couldn't live like that.
I finally quit taking met about 2 months ago. Within a couple of days, the entire problem went away. I'm completely normal in that area again. But, my bs started climbing even though I eat under 30 grams of carbs a day. I ended up taking glyburide, and while it's helping to keep my bs down, I'm gaining weight like crazy and am freaking out over that.
I'm hoping you get some great answers/responses as I'm not happy with the glyburide.
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Old 07-10-2013, 09:27 PM   #3
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oh, I am so sorry about the Metformin, both of you. that is terrible. I remember the first month I took it it felt like rocks in my stomach the whole time, but I adapted...

I would NOT take januvia. Please look at the BloodSugar101 site about that class of drugs. Some new studies are pretty alarming about them causing abnormal pancreatic cells that can become cancerous. it's not conclusive since they are pretty new and these things don't happen overnight, but I am convinced...

actually, insulin is the best solution to my way of thinking. I know that is not what you want to hear, but it's so much better for you than pills that alter pancreatic cells trying to get it to produce more insulin than is natural for you. it is not hard to use if you get the pens where you just dial the number of units. the needles are so small they don't really hurt...

think about it *hug*
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Old 07-11-2013, 05:41 AM   #4
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I had the same reaction to Metformin along with serious crashes. My doctor finally suggested putting me on insulin to not only control my BG levels but also to give my pancreas a break. I used the little pens so no pain of injections and so easy to set the doseage. For awhile I took Lantus once a day and Humalog at meals.
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Old 07-12-2013, 11:31 AM   #5
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Januvia

Long and windy about Januvia.

Would also definitely stay away from Januvia, having read a lot about its potential to causing pancreatic problems -- especially pancreatic cancer!

Several mos ago my doctor, seeing Met wasn't cutting it for me because of high readings, then gave me 6 wks' samples of Januvia. Asked him what are the side effects of it...he looks at me and has the audacity to say 'there are no side effects.' Unfortunately I trusted him!!!!!

W/some hesitation (wasn't sure why, something didn't set right w/me from the get-go in taking Januvia and I hesitated a few days after getting the samples in taking them) started taking Januvia (this was before realized this doctor was not telling me the truth, etc., about the side effects) and my blood sugar readings came down nicely. WOW...I was impressed but still a bit nervous because wasn't sure about this med. But I let my trust in this doctor override my gut feelings.

A friend of mine was even in support of taking Januvia and told me one of the 'side effects' that she had read about was that it was good for the heart. I thought SHE knew what she was talking about as her father was a pharmacist. This friend is always doing research on all kinds of meds . But guess what...she missed telling me that it's known to cause pancreatic cancer. Good grief.

After taking the Januvia samples for around 4 weeks, got a bit MORE nervous (that gut feeling again) about it so was moved to do some looking around about it online on my own. So because of seeing what several others were saying about it stopped it for a few wks (saw my sugar readings go right back up again of course ).

A few wks after I had quit taking Januvia, my husband has his appointment to get bloodwork checked and he finds out HE has diabetes and tells his doctor what I was taking and asked about it. HIS doctor tells him to tell me 'STAY FAR AWAY from Januvia because it's dangerous stuff!' Yikes!

Before hearing that, though, spoke to the pharmacist at the pharmacy we go to, and he told me Januvia is a kind of trade off for sugar-related issues for cancer, and stressed that the dangers of high blood sugar outweighed the side effects from the Januvia. Some trade off, huh? Though he wouldn't come right out and say 'don't take it' for some reason (???). Asked the pharm (sounded very young as in 'inexperienced') for a med he recommended to replace the Januvia and he came up with something that was newer also. Looked this one up...same thing! Bad side effects. The name of that one was Onglyza.

This is definitely a big cover up regarding the drugs causing pancreas problems that are now being prescribed to diabetics! Usually the pharmacists will tell you like it is regarding meds, but this one wasn't doing so. Another disappointment!

A friend of mine who is a long-time diabetic and who is up on all the newest diabetic meds had never even heard of Januvia when asked about it a couple mos ago. He was on Actos about 2 years ago, and this one also seems to be causing lots of pancreas problems, including cancer. In fact, his wife had expressed concerns to me about her husband taking this newer one because of the pancreatic cancer problem.

It made me nervous that this diabetic friend, who goes to a specialist that is quite a distance away, and who was well acquainted w/diabetic meds, hadn't heard of Januvia yet. Definitely NOT a 'good sign.'

Metformin isn't cutting it for me. Was on 1500 for a few weeks (before Januvia) but that didn't help as much as the doctor wanted for me, so that was when my doctor had me stay on 1500mg Met AND told me to take the 6 wks of Januvia samples. So...Wondering what to do next. Sure can't rely on this doctor for being truthful about Januvia (or the pharmacist, for that matter). What else is new, right?

Has anyone tried others that have helped that don't have this 'history' like Januvia and Actos and that are are working in lowering blood sugar readings for them? And are these you may mention usually taken in addition to Metformin?

By the way, am also doing low carbing in addition to currently taking the Met. Still running around 150 fasting a.m.

So far two doctors and a nutritionist have highly recommended doing this way of eating (low carb). Well, one thing good has come out of all this...my husband and I are now on the 'same page' with our meals.

Thanks for any help out there!

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Old 07-14-2013, 08:12 PM   #6
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Aw I'm so sorry Metformin didn't work for you - I had to give it up for the same reasons, and Byetta made me vomit constantly. I finally starting using Levemir insulin twice a day, and had no side effects at all. And now that I'm keeping my carbs really low, I'm not taking anything and still keeping my BG under 100. Good luck and hugs to you.
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Old 07-15-2013, 06:14 PM   #7
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How many mg are you taking? I can't not handle more than 1500 a day and sometimes no more than 1,000. Maybe you just need to decrease your dosage?
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Old 07-22-2013, 04:55 AM   #8
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Chocolate Rose – Yes! I’ve missed out on so many social events because of this one little pill.

Anne Frank – It makes me so angry when I think of how doctor’s downplay or completely ignore the side effects of the crap they prescribe. Makes you feel like they are more about keeping you drugged up (and coming back as a result of all the side effects) than truly helping you care for your health. I have yet to find a doctor who cares more about healing than flipping out their prescription pad. I will not let any doctor prescribe a drug without researching it first. Even though my health is not all that great and I could do more to restore it, I’m not going to blindly trust anyone when it comes to taking something that could make my situation worse.

Ravenrose & Doxielove & Aomiel – I am planning on discussing insulin with my doctor on my next visit (August 5th). Did it make you gain weight? I’m already 100+ lbs overweight, the last thing I want is to pile on more pounds.

MisticalMisty – I currently take 1500mg. 500 in the morning and 1000 at night. Strangely, it is the morning dose that sets me off. The nighttime dose doesn’t bother me at all.
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Old 07-22-2013, 12:48 PM   #9
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I was taking the ER ones and still had issues. I was somewhat dealing with those issues and then it got too much when I was having bloody stools. I went off of it and really watched my diets. Had a good A1C test, and now because I know I need to keep it under control I'm really being good about what I eat.

When I went for my follow-up my doctor mentioned that they were coming out with a new form of Metformin that should take those stomach issues away. I don't know how soon that is though.
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Old 07-22-2013, 03:36 PM   #10
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MisticalMisty – I currently take 1500mg. 500 in the morning and 1000 at night. Strangely, it is the morning dose that sets me off. The nighttime dose doesn’t bother me at all.
My endo told me that it doesn't really matter when you take it...so maybe speak with your doc and try to take them all at night or move it to an afternoon dose and then an evening dose

I have a great relationship with my doctor and he lets me control dosage, time, meds, etc. I play around, find what works for me, and report back to him. I would try something until you find what works for you!
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Old 07-22-2013, 07:25 PM   #11
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When I went for my follow-up my doctor mentioned that they were coming out with a new form of Metformin that should take those stomach issues away. I don't know how soon that is though.
I'd love to know more about this. If there was a form of metformin that I could tolerate, I'd switch back to it in a heartbeat!
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Old 08-05-2013, 09:31 AM   #12
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Glipizide

I have been on glypizide since 2003. No side effects. Just read Dr. Bernstein and trying to follow. I see a difference already but changing 50 years of eating carbs is a challenge. I think glypizide is an older drug. Doctors push the latest drugs the pharmaceutical reps try to get them to use.
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Old 08-05-2013, 08:54 PM   #13
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I took it for about a week and it constipated me (go figure). I have two doctors that tell me I should take it for PCOS, and my Endo said I shouldn't. They wanted me to give it another try, the Endo doesn't. I don't know what to do. I'm contemplating.
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Old 08-06-2013, 03:10 AM   #14
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Ok time for an update guys. I saw my dr yesterday and she wants me to research one more oral medication before referring me to an endocrinologist for insulin. She gave me a month's worth of samples of Onglyza to try if I decide to take it. I've only read one article on this drug so far and I'm not liking it either. Seems like it could have the side effects of Januvia (pancreatic problems) along with possibly causing migraines, skin rashes and immune suppression, upper respiratory and urinary tract infections.

I dont have the strongest immune system... I get upper respiratory infections all the time and need no help there! So I don't think I will be taking this one either.

I will call and let her know Im going to need insulin.
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Old 08-06-2013, 05:32 AM   #15
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I am planning on discussing insulin with my doctor on my next visit (August 5th). Did it make you gain weight? I’m already 100+ lbs overweight, the last thing I want is to pile on more pounds.
Initially, yes...about 8 pounds *BUT* my doctor warned me about this and explained that if I did, it was because I was most likely no longer sugar dumping through my urine so now my excess calories were going to turn to fat. I went low carb about the same time I started insulin though and that 8 lbs *plus* more came off pretty quickly. I know it sounds scary to gain weight but keep in mind that if you do, it's not the insulin causing the weight gain, but excessive carbs.

If you've been doing low carb, you may not even see any type of weight gain.
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Old 08-06-2013, 12:56 PM   #16
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Diabetes medicine side effects

I am on several medicines for arthritis. They alone cause constipation. I was on insulin, but improved my numbers and stopped taking. I am on glypizide twice a day.

I purchased bran tablets from HSN Andrew Lessman. They come in capsule form. You can also purchase capsules and tablets at GNC. You have to experiment how many you need. It is different with everyone. It is just some type of bran or psyllium husk in a capsule.

Insulin may have made it harder for me to lose, but I have to say, though, that for me I was not following any program totally. If I was on Weight Watchers I cheated or forgot to track points. If I was on calorie counting I did the same. If I tried no/low carbs I cheated. I have to face it that I love food waaaay too much.

When I stick to any diet (really stick to it), the weight does come off. That is my life story right there. I do not stick to a plan. Now my blood sugar is out of control if I don't limit the carbs. I also have to eat small amounts of food low carb or not.

I loved the original thought that Dr. Atkins showed in his books of people consuming calories in the 2000 range and above and able to lose. For me, large amounts of anything including low carbs makes my blood sugar go up.

If I get busy and don't eat my numbers go up. If my morning numbers were in the 80's, my body sends out an alert and up it goes if I don't eat. For me I have to eat small amounts throughout the day and a little more for dinner.

It is depressing to have to spend so much time on food. You do have to be your own doctor also. They mean well, but most doctors are not that up on diabetes. They want you to eat the very thing (carbs) that causes your blood sugars to sky rocket.

Maybe some day they will find a cure.
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Old 08-21-2013, 09:12 AM   #17
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If you really want to get off meds and control your bs you should try the Diabetes Miracle diet by Diane Kress......her's is the best diet to be on to maintain bs control. People have been able to get off their meds by sticking with this diet.
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Old 08-21-2013, 03:29 PM   #18
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I've read Kress' book and wasn't impressed. If you really want to get off meds (or at least have the chance of), I'd recommend Dr. Bernstein's "Diabetes Solution". Dr. Bernstein has been treating diabetics, both type 1 and type 2 for over 40 years.

Type 1 will always have to take insulin. Type 2 *might* be able to stop taking meds eventually, but it all depends on how overworked your pancreas was.

Following Dr. Bernstein's plan of only protein and non-starchy vegies with a max of 25gm of carbs per day, spread across your meals (4-5 at breakast, 10 for lunch, 10 for dinner). No fruits, grains, starches. Protein limited to 1-1.5gm per kilo of ideal weight (this one may vary by individual) because excess protein can cause blood glucose spikes.

I went from uncontrolled even with maximum doses of Lantus and high doses at meals and still struggling to get my BG under 250 (because I was still eating carbs) to off all medications within 6-8 weeks.
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Old 08-21-2013, 06:13 PM   #19
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Congratulations on your accomplishment Aomiel! That is fantastic! The reason I like Kress's book is because she makes sense about eating something ever 5 hours to control the liver from dumping glycogen automatically. I'll have to get Bernstein's book now too....sounds like his plan is more like atkins though.
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Old 08-22-2013, 07:02 AM   #20
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Congratulations on your accomplishment Aomiel! That is fantastic! The reason I like Kress's book is because she makes sense about eating something ever 5 hours to control the liver from dumping glycogen automatically. I'll have to get Bernstein's book now too....sounds like his plan is more like atkins though.
Ibryt,

Somewhat in that they're both low carb. The biggest difference between Atkins and Bernstein though (since Bernstein is focusing directly on controlling BG through diet as much as possible) is that Bernstein doesn't advocate increasing carbs, considers fruits/grains/starches off limits and unnecessary for diabetics and also controls quantity of protein since excess can also cause BG spikes. Oh, and Bernstein does do lower fat but I ignore that since I know that higher fat is not an issue with diabetes.

I did try increasing my carbs by about 5 at lunch and dinner just so I could have a bit more vegies, but found that 5 extra carbs made a difference in my BG. Now some would say a BG of 105 is no big deal, but my goal is to stay around 90.

This past week I decided to do bullet proof coffee for breakfast (250gm of coffee with 2 Tbs kerrygold butter blended into it) instead of my usual eggs to see if lowering my daily protein made any difference. Instead of eating around 63gm daily, I'm at about 50. My fats increased to a steady 71% (from 60-65) but my BG has dropped from about 90 to a rather consistent mid-80's!
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Old 08-22-2013, 10:19 PM   #21
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Aomiel, may I ask why you try to keep your BG around 90? I like to keep under 110 2 hours after a meal, and my a1c is the equivalent of 105, but wonder why you target so much lower? Are there health effects at my levels?
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Old 08-23-2013, 06:37 AM   #22
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Aomiel, may I ask why you try to keep your BG around 90? I like to keep under 110 2 hours after a meal, and my a1c is the equivalent of 105, but wonder why you target so much lower? Are there health effects at my levels?
No reason other than if 'normal' is 90, then that's what I aim for. The Mayo Clinic and others consider a normal A1c to be between 4.5-6. Yet they say between 5.7-6.4 is pre-diabetes. It doesn't make sense to me that a 'normal' goes up to 6, but they consider 5.7 to be pre-diabetic. Plus, they 'accept' a level of 7 (which means BG's of over 150!) for those already diagnosed as diabetics. Huh? Seems to me they should be aiming for the highest standards and adjusting from there.

My goal when I started was to get to as close to 'normal' as possible, not knowing whether my pancreas was going to let that happen. So I follow Dr. Bernstein (except that his is low fat and with carbs under 25, I know I don't need to do low fat).

I have found that protein has a very dramatic effect on my BG...more so than just adding a couple extra carbs of green vegies. Interestingly, this past week or so I've traded off either my breakfast or lunch of eggs & sausage or 4 oz of protein for a BPC (250mg coffee with 2 Tbs of Kerrygold butter blended into it) and my BG has dropped from pretty consistent 90-95 down to a consistent mid-80's. I did this to see what would happen if I dropped my protein grams...and the side benefit to the BPC as a meal is that it keeps me satisfied for 6-7 hours. Surprising, but love it!

I don't know that I'd recommend someone trying to drop this low while still on meds (and this may be why doctors standards are higher for diabetics) since you might run the risk of the med dropping you too low. However, I'm not on meds so it works for me.
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Old 08-23-2013, 07:00 AM   #23
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That is interesting, I just started the bullet proof coffee only using coconut oil instead of butter. I just use a teaspoon of oil. I heard using coconut oil is just as good only I don't really know how much to use, 2 Tbs seems like a lot. Anyway, so you are not eating any carbs but veggies and going as much as 6 or 7 hours without eating after you drink your coffee? Have you had an A1c lately? I'm curious if drinking the BPC will lower it even more.
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Old 08-23-2013, 07:14 AM   #24
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Sorry to hear about your Metformin experience.

I was taking regular Met a couple years ago up to 2000mgs a day.......like you I was HORRIBLE.........I eventually quit taking it, controlling or trying to control it with diet and exercise. Eventually my numbers crept back up. I actually changed doctors within the group and she put me on the ER version on only 500MG a day. It was working, but last time I asked to up it to 1000mg a day. I have had NO problems, it is like a God send for me.

Around the same time I had a colonoscopy and had two pre-cancerous polyps. I added some benefiber only 2 tsps once a day and I"m not sure if THAT's what helped or not. It's supposed to form a gel in the lower intestines and help with going too much or constipation.

Anyway wanted to through out the taking a fiber supplement and drinking water to you.
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Old 09-09-2013, 03:32 PM   #25
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I have been on metformin 1000 mg for over a year and it tears me up too so I feel your pain! I stopped taking it last week (on my own because I am tired of being sick) I went back to normal. I hadn't felt that great in a long time! I was trying to control with just diet this past week but it's not working. My fasting this morning was 170 So I started taking my metformin again today I go back to the doctor next week, he also had me on victoza but I read all kinds of scary stuff about that so I stopped taking that last week as well. (not going to start taking that one again)

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Old 09-09-2013, 06:36 PM   #26
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I have been on metformin 1000 mg for over a year and it tears me up too so I feel your pain! I stopped taking it last week (on my own because I am tired of being sick) I went back to normal. I hadn't felt that great in a long time! I was trying to control with just diet this past week but it's not working. My fasting this morning was 170 So I started taking my metformin again today I go back to the doctor next week, he also had me on victoza but I read all kinds of scary stuff about that so I stopped taking that last week as well. (not going to start taking that one again)
I'd love to know what you end up doing as I'm in the same boat.
I'm on glyburide and not very happy about it. And, it's not really helping me much.
My dr appt is next week and I think some big decisions are going to have to be made.
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Old 09-10-2013, 09:04 AM   #27
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Chocolate Rose and ItsOverSugar:

Just wondering how your BG levels would be if you dropped the met and went almost ZC?
I have severe crohns so I know all about your good friends Al and Ed (anal leakage and explosive diarrhea). With urgency and Ed in your life, you have no QOL. ZC is a small price to pay.

If your numbers were still up, you may be forced into low dose insulin. Mu mom has type 2 and had to stop met too. She's an insulin dependent diabetic, but sadly will not/cannot shake her addiction to sugar and wheat. And now with the cancer I feel like she thinks it's her only joy left. It's so hard to stand by and watch :,(
Take good care, ladies.
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Old 09-11-2013, 08:30 AM   #28
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That is interesting, I just started the bullet proof coffee only using coconut oil instead of butter. I just use a teaspoon of oil. I heard using coconut oil is just as good only I don't really know how much to use, 2 Tbs seems like a lot. Anyway, so you are not eating any carbs but veggies and going as much as 6 or 7 hours without eating after you drink your coffee? Have you had an A1c lately? I'm curious if drinking the BPC will lower it even more.
My last A1c was July so she won't test it again until probably November since it was so good and I'm being consistent.

I like the butter because I love the taste over just oil (whipped in a blender).

No, after reading 'Trick or Treat', I've pretty much gone no vegies. Occasionally I'll have a romaine salad *or* some fresh green beans with garlic butter, but I don't stress about adding those vegies anymore.

Yes, I'm guessing my A1c will go down further because when I was around 90 (roughly), it was 4.9. Now I'm running around 80-84. The BPC seems to be lowering my BG, most likely because there's no protein in it vs the protein in the 2 eggs and bacon that I would normally have had...and the protein seems to have a very direct affect on my BG's.
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Old 09-11-2013, 08:35 AM   #29
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For those who worry about having to go from an oral to insulin...seriously, it was the best decision I ever made. I took Lantus 2x a day which kept my BG's very stable and it was easy to adjust to reach the point where I was getting consistent before and after (meals) numbers, as well as a decent fasting.

Instead of forcing your pancreas to push the insulin you need, meds like Lantus help you along, giving your pancreas a break so it doesn't burn out completely. You can get it in the little pens (don't forget to tell the doc to write a prescription for the needles because some chucklehead doesn't think you need the needles to go with the pens ) so it's very easy to give and not painful like the syringes.

Rather than going on any oral meds, I continued with the Lantus even when I was down to only taking 5 units in the morning and evening and then just quit meds completely. Only possible, IMHO, by following Dr. Bernstein's diet.
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Old 09-11-2013, 07:07 PM   #30
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Originally Posted by Natalia View Post
Chocolate Rose and ItsOverSugar:

Just wondering how your BG levels would be if you dropped the met and went almost ZC?
I have severe crohns so I know all about your good friends Al and Ed (anal leakage and explosive diarrhea). With urgency and Ed in your life, you have no QOL. ZC is a small price to pay.

If your numbers were still up, you may be forced into low dose insulin. Mu mom has type 2 and had to stop met too. She's an insulin dependent diabetic, but sadly will not/cannot shake her addiction to sugar and wheat. And now with the cancer I feel like she thinks it's her only joy left. It's so hard to stand by and watch :,(
Take good care, ladies.
Hi Natalia,
The day I was diagnosed, I gave up carbs. I read everything I could online about lc and found out about LCHF. So, that's what I've been doing ever since. I also bought and read Bernstein's book. It'll be 2 years in February. I keep my carbs under 30 a day and oftentimes even lower. I gave up met a few months ago and haven't had any intestinal issues since then (no Al or Ed). That was when I was put on glyburide. I resisted the glyburide for about a week and a half and watched my bs go up up up, even on vlc. I'm just sad that I'm not one of those who can control it through diet alone. Giving up the met made it possible for me to have a life again, but it looks like I'm going to have to get into even more drugs. I heard somewhere that a new met is being developed that is supposed to be easier on your intestines. I wish they'd make it available now.
Sorry your mom is having such a hard time. Giving up carbs was hard for the first few days, but then the cravings went away. Sometimes it's an inconvenient way of eating, but I enjoy being able to eat fat with no guilt.
Have you given her any info on how cancer cells feed on sugar? LC is supposed to be beneficial when dealing with cancer.
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